TRANSCRIPTOME-WIDE PROFILES OF CIRCULAR RNA AND RNA-BINDING PROTEIN INTERACTIONS REVEAL EFFECTS ON CIRCULAR RNA BIOGENESIS AND CANCER PATHWAY EXPRESSION

Transcriptome-wide profiles of circular RNA and RNA-binding protein interactions reveal effects on circular RNA biogenesis and cancer pathway expression

Abstract Background Circular RNAs (circRNAs) are stable, often highly expressed RNA transcripts with potential to modulate other regulatory RNAs.A few circRNAs have been shown to bind RNA-binding proteins (RBPs); however, little is known about the prevalence and distribution of these interactions in different biological contexts.Methods We conduct

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Rare Recurrence of Sydenham Chorea in an Adult: A Case Report

Gashaw Solela, Medina Fedlu Department of Internal Medicine, Yekatit 12 Hospital Medical College, Addis Ababa, EthiopiaCorrespondence: Gashaw Solela, Tel +251 921562995, Email gashawsol@gmail.comBackground: Sydenham chorea is thought to be an autoimmune condition that usually develops following a group A beta-hemolytic streptococcal infection.The o

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